产品名称
SNRPC Rabbit Polyclonal Antibody
蛋白名称
U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6631
Human Swissprot No.
P09234
Human Swissprot Link
https://www.uniprot.org/uniprot/P09234
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20630
Mouse Swissprot No.
Q62241
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q62241/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361808
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D3ZCL3/entry
特异性
This antibody detects endogenous levels of SNRPC at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
