产品名称
PCID2 Rabbit Polyclonal Antibody
蛋白名称
PCI domain-containing protein 2 (CSN12-like protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55795
Human Swissprot No.
Q5JVF3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5JVF3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=234069
Mouse Swissprot No.
Q8BFV2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BFV2/entry
特异性
This antibody detects endogenous levels of PCID2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus, nuclear pore complex .
功能
Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (Probable). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells .
