产品名称
MYO9A Rabbit Polyclonal Antibody
蛋白名称
Unconventional myosin-IXa (Unconventional myosin-9a)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4649
Human Swissprot No.
B2RTY4
Human Swissprot Link
https://www.uniprot.org/uniprot/B2RTY4
Mouse Swissprot No.
Q8C170
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8C170/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171296
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z1N3/entry
特异性
This antibody detects endogenous levels of MYO9A at Human,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Found to be expressed in testis and placenta and at lower levels in all the examined tissues with the exception of liver (PubMed:10409426). Isoform 5: Found in leukocytes but not in brain, retina or testis (PubMed:10409426).
细胞定位
Membrane ; Single-pass membrane protein . Cytoplasm . Cell junction, synapse . Cell projection, growth cone . Localized in the cytoplasm of cell bodies, dendrites and axons with occasional hints of an enrichment near the plasma membrane. Localized at the neuromuscular junction (By similarity). .
功能
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance (By similarity).
