产品名称
LRMP Rabbit Polyclonal Antibody
蛋白名称
Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4033
Human Swissprot No.
Q12912
Human Swissprot Link
https://www.uniprot.org/uniprot/Q12912
Mouse Swissprot No.
Q60664
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60664/entry
特异性
This antibody detects endogenous levels of LRMP at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells. Expressed in germinal center B-cells, splenic marginal zone cells and B-cell lymphomas. Expressed in neuronal cells in the cerebral cortex, epithelial cells in tonsil, adrenal glands, zymogen-producing cells in the stomach and epithelial cells in seminal vesicles.
细胞定位
[Processed inositol 1,4,5-triphosphate receptor associated 2]: Cytoplasm .; Endoplasmic reticulum membrane ; Single-pass type IV membrane protein . Nucleus envelope . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Chromosome . Colocalized with ITPR3 on the endoplasmic reticulum membrane. .
功能
Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules.
