产品名称
FAM168B Rabbit Polyclonal Antibody
基因名称
FAM168B KIAA0280L MANI
蛋白名称
Myelin-associated neurite-outgrowth inhibitor (Mani) (p20)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=130074
Human Swissprot No.
A1KXE4
Human Swissprot Link
https://www.uniprot.org/uniprot/A1KXE4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=214469
Mouse Swissprot No.
Q80XQ8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80XQ8/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=690188
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D4AEP3/entry
特异性
This antibody detects endogenous levels of FAM168B at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level). Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level).
细胞定位
Cytoplasm, perinuclear region . Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Expressed in neuronal cell bodies and axonal fibers. .
功能
Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27.
