产品名称
C12orf65 Rabbit Polyclonal Antibody
蛋白名称
Probable peptide chain release factor C12orf65, mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=91574
Human Swissprot No.
Q9H3J6
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H3J6
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72650
Mouse Swissprot No.
Q80VP5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80VP5/entry
特异性
This antibody detects endogenous levels of C12orf65 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in all areas of the brain tested.
功能
Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation . As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue .
