产品名称
BPI Rabbit Polyclonal Antibody
蛋白名称
Bactericidal permeability-increasing protein (BPI) (CAP 57)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=671
Human Swissprot No.
P17213
Human Swissprot Link
https://www.uniprot.org/uniprot/P17213
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=329547
Mouse Swissprot No.
Q67E05
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q67E05/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=296321
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AXU0/entry
特异性
This antibody detects endogenous levels of BPI at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Restricted to cells of the myeloid series.
细胞定位
Secreted . Cytoplasmic granule membrane . Membrane-associated in polymorphonuclear Leukocytes (PMN) granules. .
功能
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
