产品名称
TRIM26 Rabbit Polyclonal Antibody
蛋白名称
Tripartite motif-containing protein 26 (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7726
Human Swissprot No.
Q12899
Human Swissprot Link
https://www.uniprot.org/uniprot/Q12899
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22670
Mouse Swissprot No.
Q99PN3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99PN3/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=309586
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P62603/entry
特异性
This antibody detects endogenous levels of TRIM26 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus . Viral infection mediates TRIM26 nuclear translocation. .
功能
E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
