产品名称
TRMT5 Rabbit Polyclonal Antibody
蛋白名称
tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57570
Human Swissprot No.
Q32P41
Human Swissprot Link
https://www.uniprot.org/uniprot/Q32P41
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=76357
Mouse Swissprot No.
Q9D0C4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D0C4/entry
特异性
This antibody detects endogenous levels of TRMT5 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion matrix . Nucleus . Cytoplasm . Predominantly in the mitochondria and in the nucleus. .
功能
Involved in mitochondrial tRNA methylation . Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
