产品名称
RGS9 Rabbit Polyclonal Antibody
蛋白名称
Regulator of G-protein signaling 9 (RGS9)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8787
Human Swissprot No.
O75916
Human Swissprot Link
https://www.uniprot.org/uniprot/O75916
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19739
Mouse Swissprot No.
O54828
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O54828/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29481
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P49805/entry
特异性
This antibody detects endogenous levels of RGS9 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors).
细胞定位
[Isoform 3]: Membrane; Peripheral membrane protein. Isoform 3 is targeted to the membrane via its interaction with RGS9BP. .
功能
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
