产品名称
KIAA1033 Rabbit Polyclonal Antibody
蛋白名称
WASH complex subunit 7
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23325
Human Swissprot No.
Q2M389
Human Swissprot Link
https://www.uniprot.org/uniprot/Q2M389
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=319277
Mouse Swissprot No.
Q3UMB9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UMB9/entry
特异性
This antibody detects endogenous levels of KIAA1033 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
