产品名称
GAN Rabbit Polyclonal Antibody
蛋白名称
Gigaxonin (Kelch-like protein 16)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8139
Human Swissprot No.
Q9H2C0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H2C0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=209239
Mouse Swissprot No.
Q8CA72
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CA72/entry
特异性
This antibody detects endogenous levels of GAN at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in brain, heart and muscle.
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton.
功能
Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
