产品名称
ESCO2 Rabbit Polyclonal Antibody
蛋白名称
N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=157570
Human Swissprot No.
Q56NI9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q56NI9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71988
Mouse Swissprot No.
Q8CIB9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CIB9/entry
特异性
This antibody detects endogenous levels of ESCO2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed in fetal tissues. In adult, it is expressed in thymus, placenta and small intestine.
细胞定位
Nucleus . Chromosome . Nuclear in interphase cells, excluded from chromosomes during metaphase but reassociates with chromosomes in telophase. .
功能
Acetyltransferase required for the establishment of sister chromatid cohesion . Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3 .
