产品名称
INPP5A Rabbit Polyclonal Antibody
蛋白名称
Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3632
Human Swissprot No.
Q14642
Human Swissprot Link
https://www.uniprot.org/uniprot/Q14642
特异性
This antibody detects endogenous levels of INPP5A at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Predominantly expressed in heart, brain, and skeletal muscle (PubMed:8006039). In brain; high level in Purkinje cells (PubMed:8013665).
细胞定位
Cell membrane ; Lipid-anchor . Cell projection, dendrite .
功能
Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate . Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity).
