产品名称
HERC4 Rabbit Polyclonal Antibody
蛋白名称
Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26091
Human Swissprot No.
Q5GLZ8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5GLZ8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67345
Mouse Swissprot No.
Q6PAV2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PAV2/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=309758
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PQN1/entry
特异性
This antibody detects endogenous levels of HERC4 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in brain and testis and detected in heart and placenta.
细胞定位
Cytoplasm, cytosol . shows a punctate cytoplasmic distribution.
功能
Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
