产品名称
SGF29 Rabbit Polyclonal Antibody
蛋白名称
SAGA-associated factor 29 homolog (Coiled-coil domain-containing protein 101)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=112869
Human Swissprot No.
Q96ES7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96ES7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=75565
Mouse Swissprot No.
Q9DA08
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DA08/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C606/entry
特异性
This antibody detects endogenous levels of SGF29 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes . SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) . In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me . Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival .
