产品名称
VISTA Rabbit Polyclonal Antibody
基因名称
C10orf54 PP2135 UNQ730/PRO1412
蛋白名称
Platelet receptor Gi24
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64115
Human Swissprot No.
Q9H7M9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H7M9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74048
Mouse Swissprot No.
Q9D659
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D659/entry
特异性
This antibody detects endogenous levels of VISTA at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in spleen. Detected on a number of myeloid cells including CD11b monocytes, CD66b+ neutrophils, at low levels on CD4+ and CD8+ T-cells, and in a subset of NK cells. Not detected on B cells (at protein level). Expressed at high levels in placenta, spleen, plasma blood leukocytes, and lung. Expressed at moderate levels in lymph node, bone marrow, fat, uterus, and trachea. Has low expression levels in other tissues.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
Immunoregulatory receptor which inhibits the T-cell response . May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation .
