产品名称
SOAT2 Rabbit Polyclonal Antibody
蛋白名称
Sterol O-acyltransferase 2 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8435
Human Swissprot No.
O75908
Human Swissprot Link
https://www.uniprot.org/uniprot/O75908
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=223920
Mouse Swissprot No.
O88908
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O88908/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=266770
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TQM4/entry
特异性
This antibody detects endogenous levels of SOAT2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expression seems confined in hepatocytes and enterocytes.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol . Plays a role in lipoprotein assembly and dietary cholesterol absorption . Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) and linolenoyl-CoA ((9Z,12Z,15Z)-octadecatrienoyl-CoA) as substrates . May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa . ; [Isoform 2]: Has lower enzymatic activity compared to isoform 1. ; [Isoform 3]: Has lower enzymatic activity compared to isoform 1.
