产品名称
SRPR Rabbit Polyclonal Antibody
蛋白名称
Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6734
Human Swissprot No.
P08240
Human Swissprot Link
https://www.uniprot.org/uniprot/P08240
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67398
Mouse Swissprot No.
Q9DBG7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DBG7/entry
特异性
This antibody detects endogenous levels of SRPR at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain. .
功能
Component of the signal recognition particle (SRP) complex receptor (SR) . Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system . Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SRP subunit SRP54 . SRP receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER .
