产品名称
ENPP4 Rabbit Polyclonal Antibody
蛋白名称
Ectonucleotide pyrophosphatase/phosphodiesterase family member 4 (E-NPP 4) (NPP-4) (EC 3.1.-.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22875
Human Swissprot No.
Q9Y6X5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y6X5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=224794
Mouse Swissprot No.
Q8BTJ4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BTJ4/entry
特异性
This antibody detects endogenous levels of ENPP4 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed on the surface of vascular endothelia.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.