产品名称
TMEM25 Rabbit Polyclonal Antibody
基因名称
TMEM25 UNQ2531/PRO6030
蛋白名称
Transmembrane protein 25
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84866
Human Swissprot No.
Q86YD3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q86YD3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71687
Mouse Swissprot No.
Q9DCF1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DCF1/entry
特异性
This antibody detects endogenous levels of TMEM25 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed throughout the brain with higher levels in the pyramidal cell layer of the hippocampal CA1 and CA3 regions. Also highly expressed within the hippocampal dentate gyrus region and cerebellum and in scattered neurons in the cerebral cortex.
细胞定位
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 4]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .; Late endosome . Lysosome .
功能
In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability.
