产品名称
DR1 Rabbit Polyclonal Antibody
蛋白名称
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1810
Human Swissprot No.
Q01658
Human Swissprot Link
https://www.uniprot.org/uniprot/Q01658
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13486
Mouse Swissprot No.
Q91WV0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91WV0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100910207
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XI68/entry
特异性
This antibody detects endogenous levels of DR1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
