产品名称
CCM2 Rabbit Polyclonal Antibody
基因名称
CCM2 C7orf22 PP10187
蛋白名称
Malcavernin (Cerebral cavernous malformations 2 protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83605
Human Swissprot No.
Q9BSQ5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BSQ5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=216527
Mouse Swissprot No.
Q8K2Y9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K2Y9/entry
特异性
This antibody detects endogenous levels of CCM2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).
