产品名称
ADHFE1 Rabbit Polyclonal Antibody
蛋白名称
Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=137872
Human Swissprot No.
Q8IWW8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8IWW8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=76187
Mouse Swissprot No.
Q8R0N6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R0N6/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362474
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4QQW3/entry
特异性
This antibody detects endogenous levels of ADHFE1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Only expressed in adult liver.
功能
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.
