产品名称
Pikachurin Rabbit Polyclonal Antibody
蛋白名称
Pikachurin (Agrin-like protein) (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=133584
Human Swissprot No.
Q63HQ2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q63HQ2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=268780
Mouse Swissprot No.
Q4VBE4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q4VBE4/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=365691
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B4F785/entry
特异性
This antibody detects endogenous levels of Pikachurin at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Secreted, extracellular space, extracellular matrix . Cell junction, synapse, synaptic cleft . Cell junction, synapse, presynaptic active zone . Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals. .
功能
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness (By similarity).
