产品名称
Nucleoside phosphorylase Rabbit Polyclonal Antibody
蛋白名称
Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4860
Human Swissprot No.
P00491
Human Swissprot Link
https://www.uniprot.org/uniprot/P00491
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18950
Mouse Swissprot No.
P23492
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P23492/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P85973/entry
特异性
This antibody detects endogenous levels of Nucleoside phosphorylase at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.
功能
Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate . Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine .
