产品名称
MPP1 Rabbit Polyclonal Antibody
蛋白名称
55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4354
Human Swissprot No.
Q00013
Human Swissprot Link
https://www.uniprot.org/uniprot/Q00013
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17524
Mouse Swissprot No.
P70290
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P70290/entry
特异性
This antibody detects endogenous levels of MPP1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell membrane ; Lipid-anchor . Cell projection, stereocilium . Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with PALS1 in the retina, at the outer limiting membrane (OLM) (By similarity). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) (By similarity). Colocalizes with NF2 in non-myelin-forming Schwann cells (PubMed:19144871). .
功能
Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
