产品名称
BZW2 Rabbit Polyclonal Antibody
基因名称
BZW2 HSPC028 MSTP017
蛋白名称
Basic leucine zipper and W2 domain-containing protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=28969
Human Swissprot No.
Q9Y6E2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y6E2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66912
Mouse Swissprot No.
Q91VK1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91VK1/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171439
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WTT7/entry
特异性
This antibody detects endogenous levels of BZW2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Translation initiation regulator which represses non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function . Increases the accuracy of translation initiation by impeding EIF5-dependent translation from non-AUG codons by competing with it for interaction with EIF2S2 within the 43S pre-initiation complex (PIC) in an EIF3C-binding dependent manner .
