产品名称
RPAP1 Rabbit Polyclonal Antibody
蛋白名称
RNA polymerase II-associated protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BWH6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BWH6/entry
Mouse Swissprot No.
Q80TE0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80TE0
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q3T1I9
免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
RPAP1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This protein forms part of the RNA polymerase II (RNAPII) enzyme complex and may recruit RNAPII to chromatin through its interaction with acetylated histones. [provided by RefSeq, Jul 2012],
组织表达
Brain,Epithelium,Eye,Mammary cancer,Teratocarcinoma,Testis,
功能
function:Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. Required for interaction of the RNA polymerase II complex with acetylated histone H3.,similarity:Belongs to the RPAP1 family.,subunit:Part of a RNA polymerase II complex that contains POLR2A, POLR2B, POLR2C, POLR2D, POLR2E, POLR2F, POLR2G, POLR2H, POLR2I, POLR2J, POLR2K, POLR2L, RPAP1, FCP1 plus the general transcription factors TFIIB and TFIIF.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
