产品名称
PAIP2 Rabbit Polyclonal Antibody
基因名称
PAIP2 PAIP2A HSPC218
蛋白名称
Polyadenylate-binding protein-interacting protein 2 (PABP-interacting protein 2) (PAIP-2) (Poly(A)-binding protein-interacting protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51247
Human Swissprot No.
Q9BPZ3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BPZ3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67869
Mouse Swissprot No.
Q9D6V8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D6V8/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361309
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AXZ0/entry
特异性
This antibody detects endogenous levels of PAIP2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed at highest level in testis, but also abundant in brain, cervix, lung, ovary, placenta, adipose tissue, thymus and thyroid.
功能
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
