产品名称
BAALC Rabbit Polyclonal Antibody
蛋白名称
Brain and acute leukemia cytoplasmic protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79870
Human Swissprot No.
Q8WXS3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8WXS3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=118452
Mouse Swissprot No.
Q8VHV1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VHV1/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140720
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q920K5/entry
特异性
This antibody detects endogenous levels of BAALC at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Predominantly expressed in neuroectoderm-derived tissues. Expressed in the brain and spinal cord, and at low levels, in the adrenal gland. In the bone marrow, confined to the CD34+ progenitor cells. Not found in peripheral blood mononuclear cells, nor lymph nodes. Tends to be expressed at high levels in acute myeloid leukemia and glioblastoma cells.
细胞定位
Cytoplasm . Cell junction, synapse, synaptosome . Membrane raft . Cell junction, synapse, postsynaptic density . In neurons, localizes to postsynaptic lipid rafts (By similarity). In myocardial and skeletal muscle cells, localizes to the cytoplasm adjacent to the inner cell membrane, polarized to one end of the myocyte (By similarity). .
功能
May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A.
