产品名称
MARF1 Rabbit Polyclonal Antibody
蛋白名称
Meiosis arrest female protein 1 (Limkain-b1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9665
Human Swissprot No.
Q9Y4F3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y4F3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=223989
Mouse Swissprot No.
Q8BJ34
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BJ34/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170946
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VIG2/entry
特异性
This antibody detects endogenous levels of MARF1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity).
