产品名称
HVCN1 Rabbit Polyclonal Antibody
基因名称
HVCN1 VSOP UNQ578/PRO1140
蛋白名称
Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84329
Human Swissprot No.
Q96D96
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96D96
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74096
Mouse Swissprot No.
Q3U2S8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3U2S8/entry
特异性
This antibody detects endogenous levels of HVCN1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen.
细胞定位
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types.
功能
Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.
