产品名称
MIOS Rabbit Polyclonal Antibody
蛋白名称
WD repeat-containing protein mio
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54468
Human Swissprot No.
Q9NXC5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NXC5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=252875
Mouse Swissprot No.
Q8VE19
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VE19/entry
特异性
This antibody detects endogenous levels of MIOS at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex . It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 .
