产品名称
BOP1 Rabbit Polyclonal Antibody
蛋白名称
Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q14137
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14137/entry
Mouse Swissprot No.
P97452
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P97452
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q562C2
免疫原
Synthesized peptide derived from human protein . at AA range: 110-190
特异性
BOP1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,
组织表达
Bone marrow,Brain,Epithelium,Eye,Liver,Lymph,Muscle,Pancreas,
细胞定位
Nucleus, nucleolus . Nucleus, nucleoplasm .
功能
function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
