产品名称
DNAJC6/AUXILIN Rabbit Polyclonal Antibody
蛋白名称
Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9829
Human Swissprot No.
O75061
Human Swissprot Link
https://www.uniprot.org/uniprot/O75061
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72685
Mouse Swissprot No.
Q80TZ3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80TZ3/entry
特异性
This antibody detects endogenous levels of DNAJC6/AUXILIN at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in various brain regions, including cerebellum, corpus callosum, cortex, striatum, brainstem, pons, putamen, spinal cord and substantia nigra. Very low expression in non-neural tissues such as leukocytes, liver, adipose tissue, skeletal muscle and bone marrow.
功能
Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons (By similarity).
