产品名称
C4BPB Rabbit Polyclonal Antibody
蛋白名称
C4b-binding protein beta chain
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=725
Human Swissprot No.
P20851
Human Swissprot Link
https://www.uniprot.org/uniprot/P20851
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q63515/entry
特异性
This antibody detects endogenous levels of C4BPB at Human,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.