产品名称
UBAC2 Rabbit Polyclonal Antibody
基因名称
UBAC2 PHGDHL1 PSEC0110
蛋白名称
Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=337867
Human Swissprot No.
Q8NBM4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8NBM4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68889
Mouse Swissprot No.
Q8R1K1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R1K1/entry
特异性
This antibody detects endogenous levels of UBAC2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets . In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 .
