BD-PN7139

SGEF Rabbit Polyclonal Antibody

常规抗体

ARHGEF26 SGEF HMFN1864

Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)

WB

Human

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

26084

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26084

Q96DR7

https://www.uniprot.org/uniprot/Q96DR7

This antibody detects endogenous levels of SGEF at Human

WB 1:500-2000

96kD

-15°C to -25°C/1 year(Do not lower than -25°C)

Isoform 1 is broadly expressed, with highest levels in liver (at protein level). Certain mRNA species appear to be specifically expressed in prostate and liver.

Cell projection, ruffle .

Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

现货