产品名称
Caveolin-3 Rabbit Polyclonal Antibody
蛋白名称
Caveolin-3 (M-caveolin)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=859
Human Swissprot No.
P56539
Human Swissprot Link
https://www.uniprot.org/uniprot/P56539
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12391
Mouse Swissprot No.
P51637
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P51637/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29161
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P51638/entry
特异性
This antibody detects endogenous levels of Caveolin-3 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed predominantly in muscle.
细胞定位
Golgi apparatus membrane ; Peripheral membrane protein . Cell membrane ; Peripheral membrane protein . Membrane, caveola ; Peripheral membrane protein . Cell membrane, sarcolemma . Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). .
功能
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae .
