产品名称
ENY2 Rabbit Polyclonal Antibody
蛋白名称
Enhancer of yellow 2 transcription factor homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56943
Human Swissprot No.
Q9NPA8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NPA8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=223527
Mouse Swissprot No.
Q9JIX0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JIX0/entry
特异性
This antibody detects endogenous levels of ENY2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus, nucleoplasm . Localization at the nuclear pore complex requires NUP153 and TPR. .
功能
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation . As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores .
