产品名称
ZWILCH Rabbit Polyclonal Antibody
蛋白名称
Protein zwilch homolog (hZwilch)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55055
Human Swissprot No.
Q9H900
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H900
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68014
Mouse Swissprot No.
Q8R060
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R060/entry
特异性
This antibody detects endogenous levels of ZWILCH at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Chromosome, centromere, kinetochore .
功能
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex .
