产品名称
DDX28 Rabbit Polyclonal Antibody
蛋白名称
Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55794
Human Swissprot No.
Q9NUL7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NUL7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71986
Mouse Swissprot No.
Q9CWT6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CWT6/entry
特异性
This antibody detects endogenous levels of DDX28 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate.
细胞定位
Nucleus . Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Mitochondrion matrix . Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. .
功能
Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function . May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity .
