产品名称
ADO Rabbit Polyclonal Antibody
蛋白名称
2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84890
Human Swissprot No.
Q96SZ5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96SZ5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=211488
Mouse Swissprot No.
Q6PDY2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PDY2/entry
特异性
This antibody detects endogenous levels of ADO at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate . Catalyzes the oxidation of cysteamine (2-aminoethanethiol) to hypotaurine . Catalyzes the oxidation of regulators of G-protein signaling 4 (RGS4) and 5 (RGS5) and interleukin-32 (IL32) .