产品名称
C11orf30 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56946
Human Swissprot No.
Q7Z589
Human Swissprot Link
https://www.uniprot.org/uniprot/Q7Z589
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=233545
Mouse Swissprot No.
Q8BMB0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BMB0/entry
特异性
This antibody detects endogenous levels of C11orf30 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
功能
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin . Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 . Mediates ligand-dependent transcriptional activation by nuclear hormone receptors .
