产品名称
RND3 Rabbit Polyclonal Antibody
蛋白名称
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P61587
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P61587/entry
Mouse Swissprot No.
P61588
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P61588
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6SA80
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
RND3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011],
细胞定位
Golgi apparatus membrane; Peripheral membrane protein.
功能
function:Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Binds ROCK1 (By similarity). Interacts with UBXD5.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
