产品名称
RND1 Rabbit Polyclonal Antibody
蛋白名称
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92730
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92730/entry
Mouse Swissprot No.
Q8BLR7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BLR7
免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
RND1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014],
组织表达
Mostly expressed in brain and liver.
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytoskeleton .
功能
function:Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Binds GRB7 and PLXNB1. Interacts with UBXD5.,tissue specificity:Mostly expressed in brain and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
