产品名称
C16orf63 Rabbit Polyclonal Antibody
基因名称
FOPNL C16orf63 FOR20 PHSECRG2
蛋白名称
LisH domain-containing protein FOPNL (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=123811
Human Swissprot No.
Q96NB1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96NB1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66086
Mouse Swissprot No.
Q9CZS3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CZS3/entry
特异性
This antibody detects endogenous levels of C16orf63 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine.
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasmic granule . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951). .
功能
Involved in the biogenesis of cilia . Required for the recruitment of PLK1 to centrosomes and S phase progression .
