产品名称
COX18 Rabbit Polyclonal Antibody
蛋白名称
Mitochondrial inner membrane protein COX18 (COX18Hs) (Cytochrome c oxidase assembly protein 18)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=285521
Human Swissprot No.
Q8N8Q8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N8Q8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=231430
Mouse Swissprot No.
Q8VC74
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VC74/entry
特异性
This antibody detects endogenous levels of COX18 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
功能
Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2. Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase).