产品名称
RBM11 Rabbit Polyclonal Antibody
蛋白名称
Splicing regulator RBM11 (RNA-binding motif protein 11)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54033
Human Swissprot No.
P57052
Human Swissprot Link
https://www.uniprot.org/uniprot/P57052
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=224344
Mouse Swissprot No.
Q80YT9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80YT9/entry
特异性
This antibody detects endogenous levels of RBM11 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain.
细胞定位
Nucleus, nucleoplasm . Nucleus speckle . Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles.
功能
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.
